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Prednisone & Weight Gain (The Studies) Many studies have been conducted to evaluate the side effect profile of prednisone and similar corticosteroid medications. Studies show that the majority of the side effect profiles are very similar to those of corticosteroids, and few studies have been conducted into the potential of the medications causing weight gain (Buch, 2001; Johnson & Lynam-Hansen, 1993; Lynam & Lund, 1988). In light of the recent increase in weight loss and obesity among middle-aged and older adults, it seems prudent to assess the potential risks of the many prescription medications and supplements commonly prescribed to overweight and obese adults and determine if they can be safely given. For more information on the side effects and potential for weight gain with certain prescription medications, see below. Most prescription medications and dietary supplements contain a range of compounds, often derived from natural sources, that contribute to a variety of biological functions and benefits including: Anti-inflammatory properties Anti-oxidant properties Antioxidant properties Gastrointestinal benefits Hormone secretion (growth hormone) Thyroid function Blood pressure regulation Antihistamines and anti-inflammatory compounds Antibiotics Glycemic-modulating medications Folic acid Antiseizure agents (such as gabapentin) Antihistamine (e.g., ketamine, yohimbine) Antiviral medications Thyroid hormone (e.g., triiodothyronine, clomiphene) Anti-inflammatory agents (e.g., aspirin, ibuprofen) Antibutans for neuropathy and arthritis (e.g., celecoxib, dacarbazine) Calcium channels Digoxin Thiamine-based peptides Cephalosporins Cimetidine Calcium-binding protein 5 (CaBP5) Calcium-binding protein 4 (CaBP4) Glycogenic acid Vitamin B-12 L-theanine Phosphatidylcholine Alarmin Sodium-potassium bicarbonate and calcium-binding agents Choline bitartrate Niacin Biotin Calcium chelate (e.g., citrate) Side effect profiles of prescription antineoplastics and cholesterol-lowering medications are also not included in most of the above table (Pugh, 2005). Side effect Similar articles: